Instruments

Q-ToF Ultima mass spectrometer

The Ultima is modified for transmission of high mass complexes. We use this mass spectrometer for the analysis of intact protein-ligand complexes to identify their stoichiometries and protein interaction modules. We can further obtain information on ligand binding and protein complex stability.

Q Exactive Plus hybrid quadrupole-orbitrap mass spectrometer aka "Schneewittchen"

We use the Q Exactive Plus for protein and lipid identification as well as advanced mass spectrometry including cross-linking or PTM analysis. The Q Exactive Plus is coupled with a Dionex Ultimate LC-system or can be operated in direct infusion mode.